We then examined the expression of TBC1D22A mRNA in IOSE-80, COC1, ES-2 and SKOV3 cell lines and found higher expression in the COC1, ES-2 and SKOV3 ovarian cancer cell lines than in the normal ovarian cell line IOSE-80 (Figure 3C). The gene discussed is TBC1D22A; the disease is ovarian carcinoma.