In addition, tumor cells need to increase their efficiency by increasing glucose transporters, or various key enzymes, such as hexokinase 2 (HK2), pyruvate kinase M2 (PKM2), lactate dehydrogenase A (LDHA), aldolase C (ALDOC), alcohol dehydrogenase gene (ADH6) [32]. The gene discussed is LDHA; the disease is neoplasm.