Alterations in the functional levels of GRK2 have been found in a variety of renal diseases, such as hypertension‐related kidney injury, sepsis‐associated acute kidney injury (S‐AKI), cardiorenal syndrome (CRS), acute kidney injury (AKI), age‐related kidney injury or hyperglycemia‐related kidney injury. This evidence concerns the gene GRK2 and Sepsis.