LRRTM4 and type 2 diabetes mellitus: However, a genome-wide sex interaction analysis identified 2 novel SNPs, which were observed to be sex-specific risk factors for the development of type 2 diabetes, showed a positive trend in the association between soy consumption and type 2 diabetes risk in men who were minor allele carriers of rs10196939 (in LRRTM4) and rs11750158 (near GFPT2).