This pilot, double-blind, randomized clinical trial explored the possible benefits of an investigational hand therapy intervention (Investigational Group) compared with a traditional occupational therapy approach (Traditional Group) to prevent CIPN in pancreatic cancer patients receiving gemcitabine (G) plus albumin-bound paclitaxel (A) containing regimens during the initial 84 days of treatment. The gene discussed is ALB; the disease is pancreatic neoplasm.