In the presence of the parasites, IFN-γ transcript levels were low in the ear lesions of both wild-type and KO mice (Table 3), while in the DLN, a fivefold increase was observed in the presence of opn (Table 3), indicating that IFN-γ-producing cells were present in the DLN after infection with the parasites. The gene discussed is SPP1; the disease is infection.