Other variants with a founder effect have been reported with hypomyelinating leukodystrophies in the Tunisian population, such as the GJC2 variant c.‐167A>G in Tunisian patients with PMLD disease (Kammoun Jellouli et al. 2013), and the FAM126 variant c.414 + 1G>T in Tunisian patients with hypomyelination and congenital cataract (Kraoua et al. 2021). The gene discussed is GJC2; the disease is leukodystrophy.