Additionally, the influence of FGF2 deletion in macrophages on sepsis was examined by depleting endogenous macrophages and reconstructing with FGF2 KO macrophages in a septic mouse model induced by cecal perforation ligation (CLP) to assess the impact and molecular mechanisms of FGF2 KO macrophages in septic ALI. This evidence concerns the gene FGF2 and Sepsis.