Notably, pancreatitis (sHR: 2.12, 95% CI: 1.14–3.95) and leukemia (sHR: 6.88, 95% CI: 2.06–22.94) were exclusively associated with long‐term GLP‐RAs (>12 months) usage when compared with the insulin group. Here, INS is linked to pancreatitis.