CD169, also known as either sialoadhesion (Sn) or sialic acid‐binding immunoglobulin‐like lectin 1 (Siglec1), is a specific marker for tissue‐resident macrophages.[6, 7, 8, 9, 10, 11, 12] Macrophages contribute significantly to tissue remodeling, angiogenesis, and combating parasitic infections. The gene discussed is SIGLEC1; the disease is parasitic infectious disease.