A similar finding has been reported by Alemu et al.8 Helminths are parasitic worms that depend on a living host for food and shelter while causing poor nutrient absorption that compromises the nourishment, and subsequently an immune response of the host.42 Studies revealed reduced numbers of T cells and their function among malnourished individuals.43,44 Thus, parasite infection could be considered as one of the predisposing factors for low BMI, resulting in reduced IFN-γ production and the progression of LTBI to active TB. Here, IFNG is linked to parasitic infectious disease.