Notably, the expression of MRGPRX2 in skin MCs was also heterogeneous, and the percentage of MCs expressing MRGPRX2 (healthy 45.40 ± 16.30%, psoriasis 39.65 ± 12.29%; Figure 4C) was similar to that of mature blood derived MCs (46.82 ± 28.66%; Figure 1A). The gene discussed is MRGPRX2; the disease is psoriasis.