DES and gastrointestinal stromal tumor: Bcl-2 and vimentin are typically immunoreactive in SFTs in addition to CD34 and STAT6, but SMA and desmin (a marker for myocytes), S-100 and synaptophysin (a marker for perineural tissue), or c-kit (a marker for gastrointestinal stromal tumors) are generally negative [4, 15, 16].