Tumor, tumor, solid, metastasis, metastatic cancer, cancer, cancer metastatic, tumors, neoplasms, neoplasm metastasis, solid tumor, advanced solid tumor, advanced cancer, malignant solid tumor, malignant solid neoplasm, malignant neoplasm, malignant tumor, TSC, TSC1, TSC2, metastatic solid tumor, metastatic neoplasm. The gene discussed is TSC2; the disease is cancer.