TP53 and neoplasm: Imaging features, including radiographic response to RT, may similarly correlate to molecular features, as seen in a recent publication that used H3K27M mutation subtype and transcriptomic profiles along with radiographic features post-RT to identify subgroups of DIPG.49 Associations between tumor mutation status (H3K27M, TP53 mutations, see Table 1) and tumor MRI volumetric features, with a particular focus on tumors with T1 enhancement, were not found in this study.