CAPN2 and pancreatic neoplasm: Moreover, overexpression of CAPN2 significantly promoted goblet cell formation (P<0.01) and cell line colony formation in pancreatic cancer organoids (P<0.001) (Fig. 4C, D and Supplementary Fig. S1E, F, G, H, Supplemental Digital Content 2, http://links.lww.com/JS9/D517).