To investigate how METTL16 affects tumor cell growth, we conducted experiments using METTL16 knockdown human pancreatic cancer-like organoids and pancreatic cancer cell lines (Supplementary Fig. S1A, B, Supplemental Digital Content 2, http://links.lww.com/JS9/D517). The gene discussed is METTL16; the disease is familial pancreatic carcinoma.