According to a study, 30.4 % of people with PDA overexpress the EGFR, and these patients have lower survival rates and lymph node metastases.[66] Another study demonstrated cytoplasmic overexpression of EGFR was found in 76 tissue samples from PDA patients, with the invasive component being more common (62 %) than the intraductal one. Here, EGFR is linked to Patent ductus arteriosus.