Besides, DUSP16 inhibition did not appear to impact Aβ deposition in either the 3xTg or SAMP8 mice, suggesting that the association between DUSP16 SNPs and MCI‐to‐AD conversion risk may be relevant to the impact of DUSP16 on hippocampal neurogenesis rather than its role in amyloid pathology. The gene discussed is DUSP16; the disease is amyloidosis.