Biallelic mutations causing immature stop codon(s) at the most N-terminal residues of KDM4B were created in two breast cancer cell lines: T-47D (Fig. 1B) and MCF-7 (Additional File 1: Fig. S2), and immunoblotting confirmed the deletion of the expression (Fig. 1C). The gene discussed is KDM4B; the disease is breast carcinoma.