TF and cancer: Baseline samples (n = 128) from the CAIRO5 cohort had a median DELFI-TF score of 25% (95% confidence interval (CI) = 21–30%), while samples from individuals without cancer (n = 153) exhibited DELFI-TF scores close to zero (non-cancer DELFI-TF = 0.09% (95% CI = 0.08–0.13%), p < 0.0001 compared to CAIRO5 baseline samples, Wilcoxon rank-sum).