A multivariate analysis model revealed DELFI-TF scores at baseline as a significant predictor of outcome, with higher HR compared to sidedness, age, CEA levels, or tumor size by SLD analyses (HR = 9.84, 95% CI = 1.72–56.1, p < 0.0001, log-rank) (Table 1). This evidence concerns the gene CEACAM5 and neoplasm.