As expected, our results illustrated that LPS and ATP determined statistically increased expression of inflammasome components, such as NLRP3, ASC, NOD2, as well as the effectors of this complex, such as caspase-1, IL-1 β, IL-18 and GSDMD, while GSDME low expression suggested the lack of treated tumor cells apoptosis. This evidence concerns the gene GSDME and neoplasm.