The structure of TAR DNA-binding protein 43 (TDP-43), associated with amyotrophic lateral sclerosis and frontotemporal dementia (Cohen et al. 2011), was studied through all-atom MD simulations at 100 and 300 mM NaCl to understand its phase separation behavior (Mohanty et al. 2024). Here, TARDBP is linked to frontotemporal dementia.