Differential expression analysis revealed that 11 ARGs were aberrantly expressed in BC, with 5 genes (TUBA1C, TUBB3, TUBB8, TUBA3D, TUBA3E) overexpressed and 6 (TUBB6, VIM, CFTR, PRKN, TUBB1, TUBB2B) underexpressed (Fig. 2A). This evidence concerns the gene PRKN and breast cancer.