NPM1 and myelodysplastic syndrome: In addition to cases of AML with NPM1 mutation, reports exist on AML with WT1 mutation,[13] AML treated with granulocyte colony-stimulating factor to induce leukocytosis,[14] AML with FLT3 mutation,[15] AML with t(11;12)(p15;q13)[16], AML with inv(11)(p15;q22), AML with MLL rearrangement,[16] and AML with MDS-like changes accompanied by 3q chromosomal deletion,[17] all exhibiting morphological and immunophenotypic similarities to APL with PML::RARA.