While the first type of tumor has characteristic gene alterations according to the specific morphological type, i.e., KRAS and BRAF mutations in serous and mucinous carcinomas and alterations in the β-catenin and PTEN genes in endometroids, type II tumors show marked chromosomal instability, and 50–80% of cases at all stages have p53 mutations, suggesting an early event in tumorigenesis [6]. Here, PTEN is linked to neoplasm.