For instance, Yu et al showed that NSCLC patients with the rs3212986 AA genotype in the ERCC1 gene have an increased risk of lung cancer, particularly among smokers.20 Gao also demonstrated that ERCC1 genotype rs11615 TT and genotype rs3212986 AA contribute to increased mortality risk from NSCLC. This evidence concerns the gene ERCC1 and lung carcinoma.