Additionally, in the combined group of ABCA and Anti‐PD1, we observed a significant decrease in the intertumoral distribution of C–C Motif chemokine 22 (CCL22), a secretory factor produced by tumor‐associated macrophages that facilitates infiltration of regulatory T cells.[46] As anticipated, the multichannel FCM analysis of Tregs revealed a remarkable reduction exceeding 60% in the Treg population within lung tumors following combination treatment with ABCA and Anti‐PD1 (Combo group), compared to treatment with Anti‐PD1 alone (Figure 6E,F). This evidence concerns the gene CCL22 and neoplasm.