We transcriptionally profiled a total of 732 Tbx18-tdT+ cells from the naïve group, 4315 Tbx18-tdT+ cells from the physical injury group (saline injections) and 2219 Tbx18-tdT+ cells from the ischemic stroke group (ET-1/L-NAME injections) (Figure 4A). The gene discussed is EDN1; the disease is ischemic stroke.