Although it is not possible to establish a direct association between SARS-COV-2 infection, MERS and hyponatremia in this patient, we believe that inflammatory cytokines, particularly IL-6, may be implicated for the following reasons: Firstly, numerous inflammatory cytokines are released during infection, which can lead to a cytokine storm and play a crucial role in the pathogenesis of SARS-CoV-2 infection (13). This evidence concerns the gene IL6 and Middle East respiratory syndrome.