SRSF7 and cancer: Finally, combining the above up-regulated genes and enriched pathways, we suggest that the C1 SRSF7+ MCs subtype is affected by the endoplasmic reticulum stress state (71), which disrupts the original protein equilibrium (72) and produces aberrant protein folding (73, 74), and this stress state dynamically reprograms the function of MCs, transforming MCs into TAMCs, which exerts pro-tumorigenic effects (75) and confers cancer cells with enhanced tumorigenic, metastatic, and drug-resistant capabilities.