In the univariable regression analysis, the risk factors of combined hypertension (OR:1.833, 95% CI: 1.243–2.704, p<0.01), history of nephropathy (OR:2.191, 95% CI: 1.125–4.267, p<0.05), family history of diabetes (OR:3.354, 95% CI: 1.957–5.747, p<0.001), CRP (OR:1.008, 95% CI: 1.003–1.013, p<0.01), NLR (OR:1.119, 95% CI: 1.034–1.211, p<0.05), GLB (OR:1.023, 95% CI: 1.007–1.038, p<0.05) and Th17/Treg ratio (OR:3.419, 95% CI: 1.549–7.547, p<0.05) increased the chances of combined T2D in patients with RA. This evidence concerns the gene CRP and kidney disorder.