Research indicates that Kaempferol, Quercetin, and Salidroside can inhibit the proliferation and migration of rheumatoid arthritis fibroblast-like synoviocytes (RA-FLSs) and mitigate inflammation and synovial damage in RA rat models through various pathways, including PI3K/AKT, MMPs, and NF-κB (15–17). Here, AKT1 is linked to rheumatoid arthritis.