JUNB and osteoarthritis: Due to the similarity between osteoarthritis and IVDD in physiopathological molecular mechanisms, biological processes such as inflammatory response, cell proliferation, and apoptosis play important roles in both diseases, JUNB gene may be involved in the process of disc degeneration, but the related mechanisms still need to be validated by further studies, and in‐depth studies can help to provide new directions and strategies for the treatment and prevention of IVDD.