HIF1A and gastric cancer: M2 TAM-derived exosomal metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) induces aerobic glycolysis in gastric cancer cells by activating the β-catenin and HIF-1α signaling pathways, enhancing their proliferation, metastasis, and chemoresistance in a glycolysis-dependent manner 71.