MAP3K7 and triple-negative breast carcinoma: An additional function of USP1 is the regulation of EMT and stem cell state, in keeping with the evidence from the literature indicating that USP1 in complex with WD repeat domain 48 enhances TGF-β induced EMT of triple negative breast cancer cells via stabilizing TGF-β-activated kinase 1 (TAK1), also known as the mitogen-activated protein kinase 7 (MAP3K7) 82.