As shown in Table S4, USP44 expression was negatively associated with T stage (P < 0.001), N stage (P = 0.002), pathologic stage (P < 0.001), age (P = 0.027), histological type (P < 0.001), extrathyroidal extension (P < 0.001) and thyroid gland disorder history (P = 0.008). This evidence concerns the gene USP44 and thyroid gland disorder.