Using TIMER 2.0 programme and GEPIA, the expression of PRDX1 was shown to be positively correlated with the expression of NRF2 (NEF2L2) and its target gene GPX4, a major scavenger of phospholipid peroxides in CRC tissues (Fig. 4G, H). This evidence concerns the gene NFE2L2 and colorectal carcinoma.