PRDX1 and infection: Thus, PRDX1 was knocked down in HCT116 and SW620 cells by lentiviral infection to generate the stable cell lines (HCT116PRDX1-KD and SW620PRDX1-KD), while PRDX1 was overexpressed in SW480 cells to generate SW480PRDX1-OE stable cells.