To further verify that it is E. coli/LPS rather than fungi after fluconazole treatment to aggravate lung inflammation during infection, we treated wild‐type C57BL/6, Dectin‐1(recognition of beta‐1,3/1,6 glucans on fungi)−/− (Figure S9A), or TLR4 (recognition of LPS)−/− (Figure S9B) mice (no change for the abundance of intestinal E. coli [34]) with fluconazole before PmCQ2 infection. The gene discussed is CLEC7A; the disease is infection.