LYPLA2P1 and cancer: The coordinated S‐acylation of Orai1 and STIM1 by zDHHC and APT enzymes might recruit both proteins to the same lipid domain to optimize Ca2+ fluxes, as suggested by studies linking enzymes involved in STIM‐ORAI1 S‐acylation/de‐acylation and cancer (Table S1).