Tumor cells of the two cases showed strong immunoreactivity for AE1/AE3, calretinin, cytokeratin 7 (CK7), podoplanin (D2-40), and weak reactivity for Wilm’s tumor gene-1 (WT1), but were negative to chromogranin A (CgA), cluster of differentiation 34 (CD34), and synaptophysin (Syn). The gene discussed is KRT7; the disease is neoplasm.