The rising prevalence of inflammation, as indicated by elevated CRP levels, aligns with the findings of other research involving preschool children in Sub-Saharan African(71,92), generally associated with recurrent acute and/or chronic infections (e.g. HIV, malaria and schistosomiasis), stunting and poor sanitation and/or poor drinking water quality(71,92,93). The gene discussed is CRP; the disease is malaria.