ACE2 and cancer: For in silico analyses we used two approaches: firstly, data from the Gene Expression Profiling Interactive Analysis 2 (GEPIA2; http://gepia2.cancer-pku.cn/#analysis) software was used to compare the expression of ACE2 between cancerous and non-cancerous breast, colorectal, and prostate tissues, the three leading cancers across all ages and genders worldwide (Fig. 1A; https://www.uicc.org/news/globocan-2020-new-global-cancer-data), and originate from cells that may be susceptible to SARS-CoV-225 aside from lung cells.