Additionally, despite IDH-wildtype diffuse gliomas being classified as HGG in this study regardless of histological grade, recent studies suggest that histologically grade 2 IDH-wildtype diffuse gliomas with isolated telomerase reverse transcriptase (TERT) promoter mutation may exhibit a more favorable outcome than glioblastoma, IDH-wildtype [34]. Here, TERT is linked to glioblastoma.