In our previous study using the stable colorectal cancer (CRC) CTC line referred to as ‘CTC‐MCC‐41’ [6] we revealed a strong activation of the PI3K/AKT/mTOR signaling pathway as well as a high susceptibility towards dual AKT/mTOR inhibition underlining the importance of this signaling pathway in this cell line for proliferation [7]. This evidence concerns the gene MTOR and colorectal carcinoma.