IL6 and Peri-Implantitis: Intracellular positive immunodetection of IL-6 can be observed in few cells in the pyramidal cell layer among the CA1 region (Fig. 5B – superior [arrow]) of the hippocampus of most of the peri-implantitis affected group slides, otherwise almost no positive IL-6 immunodetection can be observed in the healthy group slides (Fig. 5A – Superior).