TP53 and neoplasm: Colony-stimulating factor 1 receptor (CSF1R) is the receptor for CSF1, also known as macrophage colony-stimulating factor (M-CSF), which, among other functions, is involved in the differentiation of hematopoietic stem cells into macrophages [14–16] and is secreted by epithelial tumor cells after p53 inactivation [17].