PDGFC and neoplasm: In addition, Pdgfc, which promotes angiogenesis (reviewed in ref. [59]) and the immunosuppressive cytokine Interleukin 10 (Il10), that contributes to tumor immune evasion (reviewed in ref. [60]), were upregulated in Mir34aΔMye macrophages, particularly in the Mrc1+ subtype (Fig. S6A, S6B).