CGAS and cancer: We further confirmed that endogenous cGAS protein is highly detected in the nucleus of different cells, not only in cancer cells, such as SK-MEL-2, SK-MEL-28, HeLa, and HT-29, but also in not transformed cells, such as JB6 Cl41 and MH7A (Fig. 1H), indicating that cGAS protein is not mainly restricted in immune cells, but in every cells.