INS and Hyperglycemia: The metabolic parameters estimated in the studied groups revealed significant (P < 0.05) elevation of serum INS (10.1 ± 2.2 mU/ l) and c-peptide (728.1 ± 194.9 pg /ml), which improve the condition of hyperglycemia (310.9 ± 53.6 mg/ dl) detected in the untreated STZ-induced diabetic rats, as the fasting blood glucose reached to be 112.4 ± 21.3 mg/ dl, but not reaching the normoglycemic state of the negative control group (96.5 ± 9.45 mg/ dl).