EEPD1 and metabolic dysfunction-associated steatohepatitis: Given the exacerbation of DNA damage by CIH, we further conducted a genome-wide association analysis of the available genome-wide association study data and found a significant correlation between a single nucleotide polymorphism within Eepd1 and both metabolic traits and hypoxia-related traits, supporting the involvement of Eepd1 in CIH-induced NASH.