PAX5 and diffuse large B-cell lymphoma: Next, they constructed diffuse large B cell lymphoma cell line models with PAX5-TSS2 deletion and point mutations and found that both PAX5-TSS2 deletion and point mutations could enhance the interaction between PAX5 enhancer region and ZCCHC7 promoter, leading to an increase in ZCCHC7 mRNA expression without substantial decrease in PAX5 expression.